CoQ10 | Alixir Life

CoQ10

Help for the heart

  • Antioxidant that lowers probability of many health issues
  • Supports exercise performance
  • Delivered as Ubiquinol, its most bioactive form

OVERVIEW

Coenzyme Q10 (CoQ10) is a molecule produced in the body that is essential for cellular respiration and energy production. It is often recommended by doctors to people who have experienced a heart attack or have been diagnosed with fibromyalgia, which is a disease characterized by widespread muscular and skeletal pain as it has the potential to protect the blood vessels and enhance blood flow.

Our CoQ10 is produced in the United States and delivers CoQ10 in its Ubiquinol form, one of two types of CoQ10 (the other being ubiquinone). Ubiquinol is the active antioxidant state of CoQ10, which is the form naturally produced by our body and therefore is better absorbed, particularly as we age.

Product Type: 1 Softgel
Dosage: 100mg

Ingredients

Ubiquinol (Kaneka QH), Medium chain triglycerides, sunflower lecithin and beeswax; rosemary extract, natural mixed tocopherols and ascorbyl palmitate added to maintain freshness. Softgel consists of bovine gelatin, glycerin and purified water; caramel and carob extract added as a light barrier.

does not contain

milk, eggs, fish, shellfish, tree nuts, peanuts, wheat and soybeans

summary of research

  • Supports exercise performance

    Studies suggest CoQ10 has a variety of exercise benefits. It can help delay fatigue during exercise, but this may not apply to situations outside of exercise.[1] [2] It also appears to increase exercise capacity for people who have heart conditions or have just suffered heart attack.[3] Additionally it appears to reduce oxidation somewhat during exercise, although results are mixed.[4] There are also studies to suggest an increase in the maximum oxygen consumption of untrained people during exercise.[5]

     

    Research Score: Promising

  • Antioxidant that lowers probability of many health issues

    A 2014 meta-analysis of different studies found that CoQ10 not only is an essential component of cell respiration and energy production, it also is an antioxidant that lowers the probability of mitochondrial disease, cardiovascular disease, high blood pressure, heart attack, certain cancers, neurodegenerative diseases (for example Parkinson’s disease, Huntington’s disease, and Alzheimer’s disease), diabetes, and even male infertility.[6] It also reduces pro-oxidative biomarkers, which are indicators of oxidative damage in the body,[7] and appears to reduce oxidation caused by exercise.[8] Additionally, it decreases lipid peroxidation, which is a marker of damage to cell membranes, to a greater extent than other nutraceuticals.[9]

     

    Research Score: Strong

  • Decreases symptoms of Fibromyalgia

    Fibromyalgia is a chronic pain syndrome with symptoms such as chronic fatigue, migraine, and joint stiffness. People think one of its main causes is CoQ10 deficiency. Five studies found CoQ10 supplementation decreased the intensity of symptoms of Fibromyalgia.[10] [11]

     

    Research Score: Strong

  • Good for the heart and blood pressure

    Heart failure is often characterized by the heart’s muscles losing their ability to properly contract due to an energy depletion associated with low CoQ10 levels. Many studies show supplementing CoQ10 to patients with cardiovascular problems can improve their quality of life and even reduce their symptoms significantly.[12] [13]

     

    People who have insufficient blood flow and high oxidative stress can see their blood flow increase again though CoQ10 supplementation.[14] [15] There also appears to be a minor reduction in blood pressure.[16]

     

    Research Score: Strong

  • May reduce inflammation

    A 2017 meta-analysis showed CoQ10 can have a minor anti-inflammatory effect, [17] especially in people with metabolic diseases like obesity.[18]

     

    Research Score: Mixed

  • May help with fertility

    Requires more evidence to assess potency, but it does appear to reliably increase seminal motility.[19] Seminal motility is an aspect of fertility, and refers to the ability of sperm cells to move in medium (and in the womb). Increasing sperm motility can improve fertility in men who are otherwise infertile.

  • References

    1.

    https://tinyurl.com/y3ve9u6c

     

    2. Cooke M, Iosia M, Buford T, et al. Effects of acute and 14-day coenzyme Q10 supplementation on exercise performance in both trained and untrained individuals. Journal of the International Society of Sports Nutrition. 2008;5:8. doi:10.1186/1550-2783-5-8.

     

    3.

    https://tinyurl.com/y568fgpu

     

    4.

    https://tinyurl.com/y32ox4v9

     

    5.

    https://tinyurl.com/y46ovcn5

     

    6. Garrido-Maraver J, Cordero MD, Oropesa-Ávila M, et al. Coenzyme Q10 Therapy. Molecular Syndromology. 2014;5(3-4):187-197. doi:10.1159/000360101.

     

    7.

    https://tinyurl.com/yxtw5x34

     

    8.

    https://tinyurl.com/y32ox4v9

     

    9.

    https://tinyurl.com/y4hg28xq

     

    10. Cordero MD, Alcocer-gómez E, De miguel M, et al. Coenzyme Q(10): a novel therapeutic approach for Fibromyalgia? case series with 5 patients. Mitochondrion. 2011;11(4):623-5.

     

    11.

    https://tinyurl.com/yyqrj2hd

     

    12. Folkers K, Wolaniuk J, Simonsen R, Morishita M, Vadhanavikit S. Biochemical rationale and the cardiac response of patients with muscle disease to therapy with coenzyme Q10. Proceedings of the National Academy of Sciences of the United States of America. 1985;82(13):4513-4516.

     

    13. Littarru GP, Tiano L. Bioenergetic and antioxidant properties of coenzyme Q10: recent developments. Mol Biotechnol. 2007;37(1):31-7.

     

    14.

    https://tinyurl.com/y2ccec9c

     

    15.

    https://tinyurl.com/yydbrfy5

     

    16.

    https://tinyurl.com/y4mb3g89

     

    17.

    https://tinyurl.com/yxumqh46

     

    18. Zhai J, Bo Y, Lu Y, Liu C, Zhang L. Effects of Coenzyme Q10 on Markers of Inflammation: A Systematic Review and Meta-Analysis. López Lluch G, ed. PLoS ONE. 2017;12(1):e0170172. doi:10.1371/journal.pone.0170172.

     

     

    19.

    https://tinyurl.com/y65ccrrg